Noted that your pipex mailbox when accessed via TalkTalk Mail webmail is working for send and receive which is a good start as it proves the mailbox is active and working as expected.
But your email client or email app connection not working on send or receive means either that your mailbox is restricted to webmail only access or the email client is not functioning or current settings are not accepted.
Tell me if your pipex master (not alias) mailbox address is or is not added to an active TalkTalk customer MyAccount. Then tell me what device and Operating system you're using for your email software and what that email software name and version is please. A screenshot of the incoming and outgoing mail server settings is always useful to spot issues in setup. Image edit screenshots and upload here using the camera icon (desktop browser mode) above this reply area.
Heads up that I'm aware that there are current issues using Outlook for Windows (aka New Outlook) and BlueMail desktop software.
